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murine tslp  (R&D Systems)


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    Structured Review

    R&D Systems murine tslp
    Murine Tslp, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 41 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/murine+tslp/Recombinant+Mouse+TSLP+Protein/pm41593243-318-37-39
    Average 94 stars, based on 41 article reviews
    murine tslp - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Cell Culture:

    Article Title: TSLP promotes GATA3-expressing effector regulatory T cells via DC2 derived from transitional DCs.
    Article Snippet: Thymic stromal lymphopoietin (TSLP), initially described as a driver of type 2 helper T cell responses, can also act on dendritic cells (DCs) to promote the generation and accumulation of GATA3-expressing effector regulatory T (eTreg) cells in the context of cutaneous melanoma.. In this study, using an experimental mouse model with induced TSLP expression by epidermal keratinocytes combined with genetic tools, we find that TSLP drives GATA3 eTreg cells through a specific migratory DC population where the co-stimulatory molecule OX40L is required.. By conducting transcriptomic identity, lineage-traced ontogeny, surface marker expression and functional studies, we identified and characterized this DC population.

    Article Title: Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance.
    Article Snippet: A LI M EN TA R Y TR A C T ACKGROUND & AIMS: Thymic stromal lymphopoitin (TSLP) is a cytokine produced by epithelial cells that cts on dendritic cells, mast cells, T cells, and B cells.. SLP is involved in the pathogenesis of allergic inflamation in the lung and skin, but data indicate a regulaory role in the gastrointestinal tract.. We tested the funcional role of TSLP in mouse models of gastrointestinal llergy and tolerance.

    Recombinant:

    Article Title: TSLP promotes GATA3-expressing effector regulatory T cells via DC2 derived from transitional DCs.
    Article Snippet: Thymic stromal lymphopoietin (TSLP), initially described as a driver of type 2 helper T cell responses, can also act on dendritic cells (DCs) to promote the generation and accumulation of GATA3-expressing effector regulatory T (eTreg) cells in the context of cutaneous melanoma.. In this study, using an experimental mouse model with induced TSLP expression by epidermal keratinocytes combined with genetic tools, we find that TSLP drives GATA3 eTreg cells through a specific migratory DC population where the co-stimulatory molecule OX40L is required.. By conducting transcriptomic identity, lineage-traced ontogeny, surface marker expression and functional studies, we identified and characterized this DC population.

    Article Title: Inflammatory cytokine TSLP stimulates platelet secretion and potentiates platelet aggregation via a TSLPR-dependent PI3K/Akt signaling pathway.
    Article Snippet: Activated integrin αIIbβ3 was quantified through the binding of the FITClabeled mouse anti-human monoclonal antibody PAC-1 (BD Biosciences). .. The platelets were activated using recombinant human or murine TSLP (R&D Systems). .. TSLPR expression was analyzed using a PE-conjugated mouse anti-human TSLP receptor antibody (eBioscience, USA) or a PE-conjugated anti-mouse TSLPR antibody (eBioscience, USA).

    other:

    Article Title: Tumor-Derived Thymic Stromal Lymphopoietin Expands Bone Marrow B-cell Precursors in Circulation to Support Metastasis
    Article Snippet: In vitro and in vivo assays: Mouse and human B cells (10 6 cells/ml) were cultured in cRPMI supplemented with or without 50–100 ng/ml murine BAFF/Blys (R&D Systems, Minneapolis, MN), or with murine or human TSLP (R&D Systems), or 16–50% of cancer CM for 2–4 days.

    Article Title: Tumor-derived Thymic stromal lymphopoietin expands bone marrow B-cell precursors in circulation to support metastasis
    Article Snippet: Mouse and human B cells (10 6 cells/ml) were cultured in cRPMI supplemented with or without 50–100 ng/ml murine BAFF/Blys (R&D Systems, Minneapolis, MN), or with murine or human TSLP (R&D Systems), or 16–50% of cancer CM for 2–4 days.



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    KEY RESOURCES TABLE

    Journal: Cell reports

    Article Title: The microbiota and T cells non-genetically modulate inherited phenotypes transgenerationally

    doi: 10.1016/j.celrep.2024.114029

    Figure Lengend Snippet: KEY RESOURCES TABLE

    Article Snippet: Taqman Tslp murine assay , ThermoFisher , Mm01157588_m1.

    Techniques: Recombinant, Staining, Ligation, DNA Purification, Enzyme-linked Immunosorbent Assay, Cell Isolation, Generated, Expressing, Plasmid Preparation, Software, Thin Layer Chromatography, Real-time Polymerase Chain Reaction, Laser Capture Microdissection, Sterility, Microscopy